Follicular Flushing

Completed · Not applicable

Conditions studied: Fertilization

In brief

Patients with infertility often undergo in vitro fertilization (IVF) to achieve a pregnancy, which involves ovarian stimulation, monitoring of follicular growth, oocyte retrieval, sperm insemination, embryo culture and embryo transfer. The oocytes are removed during surgery by aspirating the follicles using a single lumen needle with an ultrasound to guide the procedure. There is some data that flushing the follicles with embryo culture media before aspiration using a double lumen needle increases the number of oocytes retrieved, particularly among poor responding patients for whom each additional oocyte recovered may substantially alter the outcome of that IVF cycle. The objective of the research is to evaluate the effect of follicular flushing in poor responders on IVF cycle outcomes.

Key facts

Study ID

NCT01558141

Run by

Weill Medical College of Cornell University

People needed

50

Starts

2011-09-01

Expected to finish

2013-05-01

Last updated by the study team

2019-01-14

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Pts ages 18-45 undergoing IVF
• Pts with ≤ 4 follicles that are ≥ 12mm on day of HCG

You may not qualify if…

• Pts undergoing natural cycles (i.e. those with intentionally low # of follicles)

Where it is running

• New York Presbyterian Hospital — New York, New York, United States

Full record on ClinicalTrials.gov

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