An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms

Completed

Conditions studied: Acute Rhinosinusitis, Allergic Rhinitis

In brief

This is a study to learn more about the common cold from studying the nasal secretions produced during a cold or episode of allergic rhinitis.

Key facts

Study ID

NCT01553110

Run by

Virginia Commonwealth University

People needed

41

Starts

2012-03-01

Expected to finish

2019-04-01

Last updated by the study team

2019-04-25

Who can join

Age: 12 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female subjects 12 years of age and older with acute nasal discharge fewer than 7 days or a history suggesting nasal allergic symptoms for at least 1 year. Internet access required during the course of the study. Patients must be symptomatic at screening.

You may not qualify if…

• Symptoms suggesting bacterial rhinosinusitis such as fever ≥ 101ºF/38.3ºC, facial swelling, and serve tooth pain. History of CRS or sinus/nasal surgery for this condition within 6 months before screening. History of respiratory signs and symptoms due to allergic rhinitis. Therapy with bronchodilators, nasal steroids, oral corticosteroids in the past 30 days. Therapy with antihistamines, nasal (Neti) washings, or decongestants in the past 24 hours. Use of any OTC cold or allergy medication 24 hours before study visits requires a 24 hour washout phase

Where it is running

• Virginia Commonwealth University School of Medicine — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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