Appetite Hormones in Binge Eating Disorder

Completed · Not applicable

Conditions studied: Binge Eating Disorder

In brief

This study investigates the hormones that the body produces in response to food intake and in response to stress, and the way that stress influences food intake. In particular, it compares the hormone levels and food intake of people with and without binge eating disorder. In order to find out how these appetite- and stress-related hormones are linked to brain activity, the study also includes an fMRI scan, a non-invasive procedure that looks at which regions of the brain are most active during a food-related scenario.

Key facts

Study ID

NCT01552759

Run by

New York Obesity and Nutrition Research Center

People needed

96

Starts

2007-05-01

Expected to finish

2012-01-01

Last updated by the study team

2013-03-11

Who can join

Age: 18 and older, up to 50. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI of 20-25 or 30-50
• stable weight(± 4%) for at least 3 mo
• premenopausal and have regular menstrual cycles (28 d ± 5), not be pregnant or lactating, and not be within 1 y of childbirth
• must like pizza and be willing to consume it during the ad libitum meal

You may not qualify if…

• significant medical or psychiatric conditions
• current and past 3-mo use of certain prescribed medications, especially those that could affect body weight, such as antidepressants and stimulants as well as smoking, or excess alcohol (> 3 drinks/d)
• vigorously exercise for more than 6 h/wk
• left-handed, with known claustrophobia for a scanner enclosure, or have metal implants, non-removable metallic dental retainers, pacemakers, or permanent eyeliner or large tattoos that contain metallic pigment

Where it is running

• St. Luke's Hospital — New York, New York, United States

Full record on ClinicalTrials.gov

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