Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety

Completed · Not applicable · Has a placebo group

Conditions studied: Social Intelligence

In brief

The purpose of this study is to learn more about how emotional processing may be affected by a hormone called oxytocin. Oxytocin is a hormone that occurs naturally in the body, and may play an important role in the way that the brain perceives information.

Key facts

Study ID

NCT01551303

Run by

Massachusetts General Hospital

People needed

47

Starts

2009-02-01

Expected to finish

2012-12-01

Last updated by the study team

2014-06-30

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• No current Axis I according to Diagnostic \& Statistical Manual for Psychiatry-IV excluded diagnoses as determined by MINI or Structured Clinical Interview for Diagnosis psychiatric diagnostic interview completed within the past 6 months
• Age 18 to 65
• Subjects must be able to give informed consent and be willing and able to comply with study procedures.

You may not qualify if…

• Patients with severe unstable medical illness, clinically significant laboratory findings, or serious medical illness for which hospitalization may be likely within the next three months
• Pregnant or lactating women.
• Subjects currently taking hormones, such as estrogen.
• Known hypersensitivity to oxytocin or to any of the excipients of Syntocinon Nasal spray.
• Known hyponatremia or concurrent use of diuretics.
• Subjects with a history of seizure disorder.

Where it is running

• Center for Anxiety and Traumatic Stress Disorders (CATSD) — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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