The Use of Probiotics to Evaluate Colonization With Antimicrobial Resistant Bacteria

Completed · Phase 4

Conditions studied: Infectious Disease of Digestive Tract

In brief

The purpose of this study is to evaluate the effectiveness of bacteria called Lactobacillus GG, a Probiotic, in preventing the growth of resistant bacteria in the digestive tract in patients on a ventilator.

Key facts

Study ID

NCT01551186

Run by

Washington University School of Medicine

People needed

103

Starts

2012-02-01

Expected to finish

2013-12-01

Last updated by the study team

2018-12-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults ≥ 18 years old
• Admission to the Medical ICU
• Expected to be on Mechanical Ventilation through an endotracheal tube for >48 hours

You may not qualify if…

• Pregnancy
• Immunosuppression
• Prosthetic valve or vascular graft
• Cardiac trauma
• Pancreatitis
• History of rheumatic fever
• Endocarditis or congenital cardiac abnormality
• Gastroesophageal or intestinal injury or foregut surgery during the current admission
• Oropharyngeal mucosal injury
• Placement of a tracheostomy

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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