Two-Point Measurement of Glomerular Filtration Rate by Iohexol Plasma Disappearance

Completed

Conditions studied: Renal Disease, Renal Insufficiency

In brief

The purpose of this study is to measure glomerular filtration rate (GFR) by iohexol plasma disappearance (gold standard) and measure serum Cystatin C levels (surrogate marker) in patients enrolled in our prospective study at baseline, day 100 and 1 year after hematopoietic cell transplant and determine if these levels correlate with serum creatinine and an estimated GFR using the Modification of Diet in Renal Disease (MDRD) equation and Schwartz formula in children.

Key facts

Study ID

NCT01545531

Run by

University of Washington

People needed

54

Starts

2008-09-01

Expected to finish

2016-01-01

Last updated by the study team

2017-01-04

Who can join

Age: 2 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age > 2 years
• follow-up at Seattle cancer care alliance

You may not qualify if…

• age <2 years
• history of diabetes mellitus
• inability to return to the SCCA for follow-up at 1 year
• allergy to iodine

Where it is running

• Fred Hutchinson Cancer Research Center — Seattle, Washington, United States

Full record on ClinicalTrials.gov

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