The Effect of Age on the Incidence of Postoperative Residual Neuromuscular Blockade
Completed
Conditions studied: Residual Neuromuscular Blockade in Elderly Patients
In brief
Residual neuromuscular blockade is frequently observed in the early postoperative period when patients have received a general anesthetic with muscle relaxants. At the present time it is uncertain whether certain patient populations are at greater risk for this common anesthetic complication. However, it is possible that elderly surgical patients may exhibit a higher incidence of residual neuromuscular blockade. The aim of this clinical trial is to determine the incidence of residual neuromuscular blockade in a cohort of younger (ages 18-50) and older (ages 70-90) patients undergoing surgery and general anesthesia.
Key facts
- Study ID
- NCT01545193
- Run by
- Endeavor Health
- People needed
- 300
- Starts
- 2011-06-01
- Expected to finish
- 2014-09-01
- Last updated by the study team
- 2019-09-16
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients presenting for elective surgical procedures with an expected duration greater than 45 minutes.
- ASA I to III patients ≥ 18 years of age, presenting for surgery requiring maintenance of neuromuscular blockade in the operating room, will be eligible for enrollment.
You may not qualify if…
- presence of an underlying neuromuscular disease
- use of drugs known to interfere with neuromuscular transmission (antiseizure medications, anticholinesterases, magnesium sulfate)
- renal insufficiency (serum creatinine > 1.8 mg/dL) or renal failure.
Where it is running
- NorthShore University HealthSystem — Evanston, Illinois, United States
Full record on ClinicalTrials.gov
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