Two Stepped Care Models for Posttraumatic Stress Disorder (PTSD) Among Cambodian Refugees With PTSD

Stopped early · Phase 4

Conditions studied: Posttraumatic Stress Disorder (PTSD)

In brief

This project aims to investigate the efficacy of two models to treat Posttraumatic Stress Disorder (PTSD) for Cambodian refugees in primary care. The first step in both models is giving a medication, which is a serotonin reuptake inhibitor/serotonin-norepinephrine reuptake inhibitor (SSRI/SSRN), with paroxetine being the first-line agent. For those patients who still have PTSD, the second step is either another medication or a culturally sensitive cognitive behavioral therapy (CBT). The investigators hypothesize that patients will improve in both models, but more so in the the CBT model.

Key facts

Study ID

NCT01542372

Run by

Massachusetts General Hospital

People needed

114

Starts

2012-04-01

Expected to finish

2014-03-01

Last updated by the study team

2017-05-17

Who can join

Age: 43 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• PTSD;
• PCL great or equal to 44;
• Survivor of the Cambodian genocide;
• At least 7 years old at the time of the Cambodian genocide

You may not qualify if…

• Pregnant;
• Active suicidality;
• Mental retardation;
• Organic mental disorder;
• Bipolar disorder;
• Alcohol dependence;
• Marijuana dependence;
• Unable to give conformed consent

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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