Study of Chokeberry to Reduce Cardiovascular Disease Risk in Former Smokers

Completed · Not applicable · Has a placebo group

Conditions studied: Cardiovascular Disease, Oxidative Stress

In brief

The purpose of this project is to determine whether chokeberry polyphenols mitigate cardiovascular disease risk in former smokers.

Key facts

Study ID

NCT01541826

Run by

University of Connecticut

People needed

62

Starts

2012-02-01

Expected to finish

2016-12-01

Last updated by the study team

2017-07-11

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Former smoker (previously smoked ≥3 cigarettes/day for at least 1 year, cessation for at least 6 months
• Healthy male or female between 18-65 y
• Serum clinical ranges no more than mildly elevated (serum cholesterol <240 mg/dL) and serum triglyceride (<150 mg/dL)
• Resting blood pressure <140/90 mm Hg
• Stable body weight (±5 lb) for last 2 months
• BMI ranges within normal and overweight (18.5-39 kg/m2)
• Willing to maintain normal exercise level (<7 h/wk)
• Willing to avoid exercise 24 h prior to blood sampling
• Willing to ingest a dietary chokeberry supplement or placebo (500 mg/d) daily for 12 wks.

You may not qualify if…

• Previous diagnoses of CVD, diabetes, or arthritis (except for osteo-arthritis)
• Currently being treated for cancer (i.e., chemotherapy, radiation therapy)
• Women with prescribed estrogen replacement therapy
• Practicing slimming diet
• Practicing vegetarian diet
• Currently taking vitamin or mineral supplements or plant pills
• Alcohol consumption exceeding the definition of moderate drinking (2 drinks/day or a total of 12/week for men or 1 drink/day or a total of 7/week for women)

Where it is running

• Roy E. Jones Building — Storrs, Connecticut, United States

Full record on ClinicalTrials.gov

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