Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury

Completed

Conditions studied: Mechanically Ventilated ICU Patients

In brief

The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths. The investigators seek to describe the quantity of stacked breaths by continuously recording flow, volume, and pressure waveforms routinely displayed on the vent. The investigators also seek to describe how primary ICU teams manage asynchrony documenting interventions of sedation or vent manipulation and what modality is most successful.

Key facts

Study ID

NCT01541514

Run by

University of Chicago

People needed

30

Starts

2011-07-01

Expected to finish

2013-12-01

Last updated by the study team

2014-12-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age > 18 years intubated and mechanically ventilated diagnosed with acute lung injury (ALI) or requiring mechanical ventilation for reasons other than ALI

You may not qualify if…

• neurological deficits (acute or chronic) that prevent effective diaphragm activity.
• Neuromuscular disease affecting the diaphragm
• Neuromuscular blockade

Where it is running

• University of Chicago Medical Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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