Asthma Inflammation Research

Enrolling by invitation · Early Phase 1 · Has a placebo group

Conditions studied: Asthma, Allergic Asthma, Non-allergic Asthma

In brief

The overall goal of the Asthma Inflammation Research \[AIR\] Translational Program is to create an integrated multidisciplinary team for the focused purpose of development of diagnostic and prognostic tests informative for airway inflammation, and for the design of innovative, targeted biologic therapeutics. The overarching aims of the AIR program are to conceptualize, develop, and test the next-generation therapeutics, and novel asthma diagnostic and prognostic tools that will allow us to improve the standard of asthma care.

Key facts

Study ID

NCT01536522

Run by

The Cleveland Clinic

People needed

60

Starts

2011-01-01

Expected to finish

2027-06-01

Last updated by the study team

2026-05-28

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Asthma diagnosed by a medical specialist and/or history of positive methacholine rest and/or reversibility of >10% of FEV1
• FEV1 is within acceptable limits
• Informed Consent is present

You may not qualify if…

• Diabetes (fasting blood sugar >110 mg/dL)
• Any milk allergies
• Coconut allergies
• BMI >40 kg/m2,
• Inability to maintain diet intervention
• Current smoking or smoking history of greater than 10 pack-years
• Any other significant respiratory or cardiac disease or the presence of clinically important comorbidities, including, uncontrolled coronary artery disease, acute or and chronic renal failure

Where it is running

• Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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