Effects of Transfusion of Older Stored Red Cells
Stopped early · Not applicable
Conditions studied: Sickle Cell Disease, Thalassemia
In brief
The purpose of this study is to determine the effects of transfusion of fresh and stored blood on patients. The investigators hope to test: * whether a similar effect (older stored blood is associated with worse outcomes) is seen in chronically transfused patients with hemoglobinopathies. This patient population will also allow the investigators to test whether iron- chelation therapy is beneficial in this setting. * whether washing or cryopreserving the red blood cells has any effect on this outcome. These findings may explain the immunomodulatory effects of older stored blood in patients and will help us develop safer transfusion products for patients.
Key facts
- Study ID
- NCT01534676
- Run by
- Columbia University
- People needed
- 3
- Starts
- 2012-02-01
- Expected to finish
- 2013-03-01
- Last updated by the study team
- 2016-10-05
Who can join
Age: 1 and older, up to 65. Sex: any. Healthy volunteers: accepted.
Where it is running
- Columbia University Medical Center — New York, New York, United States
Full record on ClinicalTrials.gov
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