Plasma Free Fatty Acids in Risk Assessment of Sepsis in the Emergency Department: A Prospective Pilot Study
Completed
Conditions studied: Sepsis
In brief
Plasma free fatty acids (FFAs) are thought to play a role in the generation of organ dysfunction. The investigators hypothesize that plasma FFA levels are a marker of poor prognosis in patients with sepsis. The present study will examine the relation between plasma FFA levels and severity of illness in patients with sepsis presenting to the Emergency Department. It will also examine the relation between plasma FFA levels and the risk of developing late morbidity, multiple organ dysfunction syndrome (MODS) and/or mortality during initial hospitalization and over a 30-day follow-up period.
Key facts
- Study ID
- NCT01530854
- Run by
- The Cleveland Clinic
- People needed
- 74
- Starts
- 2008-02-01
- Expected to finish
- 2012-01-01
- Last updated by the study team
- 2026-06-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- 18 years of age or older
- Able to provide informed consent (or has surrogate present that can do so)
- Presenting to the Emergency Department (ED) for evaluation
- Clinical suspicion of infection, as indicated by the ED physician's ordering a blood culture or a current temperature of ≥38C.
You may not qualify if…
- Liver disease
- Hepatitis
- Alcohol consumption >2 drinks/day for longer than 6 months
- Pregnant women
- Prisoners or other institutionalized individuals
- Unable to speak the English language
- Unwilling or unlikely to be reachable by telephone for the 30-day follow-up status assessment call
Where it is running
- Cleveland Clinic — Cleveland, Ohio, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.