PharmacoMRI of Parkinson Disease

Completed · Not applicable

Conditions studied: Parkinson's Disease

In brief

Based on studies showing better responsiveness of motor versus cognitive symptoms to Parkinson's Disease medication, also known as dopaminergic treatments, the investigators hypothesize that comparison of resting state networks in the on versus off medication state in Parkinson's Disease patients will show greater effects on brain networks associated with motor control.

Key facts

Study ID

NCT01528592

Run by

Northwestern University

People needed

18

Starts

2011-06-01

Expected to finish

2012-07-01

Last updated by the study team

2018-05-03

Who can join

Age: 30 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Idiopathic Parkinson's Disease (PD)
• Older than 30 years of age at the time of diagnosis
• Hoehn and Yahr stage greater than or equal to 2.5
• PD duration greater than 3 years
• Stable regimen of PD medications for at least 2 weeks prior to imaging
• PD medications include carbidopa-levodopa

You may not qualify if…

• Patients with a diagnosis of other neurodegenerative conditions
• Patients unwilling or unable to give informed consent
• Contraindications (cardiac pacemaker, etc.) or inability (e.g., claustrophobia) to undergo MRI scan

Where it is running

• Northwestern University — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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