Exercise Capacity in Pediatric Sickle Cell Anemia

Completed

Conditions studied: Sickle Cell Anemia

In brief

The purpose of this study is to use comprehensive exercise testing to examine causes of exercise limitation in children and young adults with sickle cell anemia.

Key facts

Study ID

NCT01527799

Run by

Ann & Robert H Lurie Children's Hospital of Chicago

People needed

60

Starts

2009-06-01

Expected to finish

2015-07-01

Last updated by the study team

2016-02-04

Who can join

Age: 8 and older, up to 21. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• age 10 to 21 years old; AND
• Hb SS or S-β0 thalassemia disease, confirmed by hemoglobin analysis

You may not qualify if…

• inability to perform maximal testing due to physical limitation (e.g. stroke or avascular necrosis); OR
• history of exercise-induced syncope or arrhythmias. Subjects will wait at least 2 weeks following any vaso-occlusive pain episode and 12 weeks following any disease-related complication requiring transfusion support. Individuals on hydroxyurea will be eligible. A total of 30 controls without SCA or sickle cell trait will be matched for age, sex and race and recruited from the siblings, friends or relatives of subjects enrolled on this study

Where it is running

• Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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