A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
Completed · Phase 4
Conditions studied: Temporomandibular Joint Dysfunction, Pain, Arthrocentesis
In brief
The purpose of this study is to determine whether the administration of hyaluronic acid or corticosteroid during arthrocentesis of the temporomandibular joint provides additional pain relief and improved function. The overall hypothesis for the study is that hyalgan will result in a 30% reduction in the mean visual analogue scale (VAS) at one month when compared to celestone and placebo.
Key facts
- Study ID
- NCT01524913
- Run by
- Emory University
- People needed
- 102
- Starts
- 2012-01-01
- Expected to finish
- 2016-04-01
- Last updated by the study team
- 2017-05-05
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- age greater than 18 years
- arthralgia of one or both temporomandibular joints
- Wilkes II to IV internal derangement of the symptomatic joint OR
- limited opening of <35 mm
You may not qualify if…
- myofascial pain as the primary source of pain
- cervical pain as the primary source of pain
- systemic arthropathy
- fibromyalgia
- use of NSAIDS within 48 hours
- allergy to study medications
- edentulous subjects
- pregnancy or breast feeding
- current physical therapy, muscle relaxants or antiseizure medications
- current use of a splint issued within last 12 weeks
Where it is running
- University California Los Angeles — Los Angeles, California, United States
- Emory University — Atlanta, Georgia, United States
- University of Cinncinati — Cinncinati, Ohio, United States
- Oregon Health Sciences University — Portland, Oregon, United States
- University of Pennsylvania — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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