Repeating Patterns of Sleep Restriction and Recovery
Completed · Not applicable
Conditions studied: Healthy
In brief
Goal of this study is to test the hypothesis that repeated exposure to cycles of insufficient sleep increases susceptibility to a variety of disease states by progressively compromising the integrity of stress response systems.
Key facts
- Study ID
- NCT01523691
- Run by
- Beth Israel Deaconess Medical Center
- People needed
- 17
- Starts
- 2011-08-01
- Expected to finish
- 2016-06-01
- Last updated by the study team
- 2017-03-14
Who can join
Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Body mass index (BMI) between 18.5 and 30 kg/m2
- For female participants: regular menstrual cycles
- Daily sleep duration in the normal range
- Blood chemistry in the normal range
You may not qualify if…
- Active infection/disease
- History of psychiatric, neurological, pain-related, immune, or cardiovascular disease; significant allergy
- Pregnant/nursing
- Respiratory disturbance index of >5 events/hour on polysomnographic sleep study, leg movements with arousal >10/hour; sleep efficiency <80%
- Regular medication use other than oral contraceptives
- Donation of blood or platelets 3 month prior to or in-between study arms
Where it is running
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
Full record on ClinicalTrials.gov
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