Study to Determine if Using Ventilation During Open Heart Surgery Improves Lung Outcomes

Completed · Not applicable

Conditions studied: Coronary Artery Disease, Heart Failure

In brief

To demonstrate that using continuous mechanical lung ventilatory support in combination with Positive End Expiratory Pressure (PEEP)during open heart surgery will improve lung function and decrease lung complications after surgery.

Key facts

Study ID

NCT01522222

Run by

Aurora BayCare Medical Center

People needed

40

Starts

2010-07-01

Expected to finish

2015-09-29

Last updated by the study team

2018-12-14

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• any patient of any gender, any age with known coronary artery disease that will undergo elective Coronary Artery Bypass Grafting (CABG) and will require CPB as part of his/her operative technique.

You may not qualify if…

• documented ejection fraction (either by echocardiogram or by cardiac catheterization) equal to or below 20%
• patients with cardiac valvular disease
• patients with a spirometry measurement that demonstrates an FEV1/FVC ratio below 60%
• patients with chronic renal failure who require dialysis or
• those who have experienced an allergic reaction to anesthesia in the past
• patients with a history of lung infiltrate on chest X-ray prior to surgery or a history of asthma
• Women who are pregnant are excluded

Where it is running

• Aurora BayCare Medical Center — Green Bay, Wisconsin, United States

Full record on ClinicalTrials.gov

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