Cvac as Maintenance Treatment in Patients With Epithelial Ovarian Cancer in Complete Remission Following First-line Chemotherapy or Second-line Treatment
Stopped early · Phase 2 · Has a placebo group
Conditions studied: Epithelial Ovarian Cancer
In brief
As \< 10% of the necessary patients required by the protocol were recruited and the data were not intended to support a labeling claim, it was determined that the abbreviated clinical study report (CSR) was the appropriate reporting format. No efficacy analyses were performed as the trial was terminated early with incomplete enrollment of \< 10%. The purpose of this study is to determine if an investigational cell therapy called Cvac can help epithelial ovarian cancer (EOC) from returning when administered to patients who are in complete remission after surgical removal of their tumor followed by standard first-line (Part A) or second-line (Part B) chemotherapy. Following remission, patients will undergo leukapheresis for the manufacture of the study agent. After completion of chemotherapy and confirmation of remission, patients will enter the treatment phase of the study.
Key facts
- Study ID
- NCT01521143
- Run by
- Prima BioMed Ltd
- People needed
- 91
- Starts
- 2012-01-01
- Expected to finish
- 2015-03-01
- Last updated by the study team
- 2016-12-14
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
Where it is running
- LAC-USC Medical Center — Los Angeles, California, United States
- Collaborative Research Group — Boynton Beach, Florida, United States
- Sarasota Memorial Hospital — Sarasota, Florida, United States
- University Gynecologic Oncology — Atlanta, Georgia, United States
- Women's Cancer Center — Morristown, New Jersey, United States
- Fred Hutchinson Cancer Research Center — Seattle, Washington, United States
- Greenslopes Private Hospital — Greenslopes, Australia
- Royal Brisbane and Women's Hospital — Herston, Australia
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.