Effects of a Dietary Fiber on Fecal Microbiota and Metabolism

Completed · Not applicable

Conditions studied: Focus of the Study is on Gut Health

In brief

The purpose of the study is to examine how a dietary fiber affects metabolism in healthy overweight and obese adults. The fiber will be added to foods that participants will consume for two, three-week periods. The fiber will be given in two doses -- 15 g per day during one period, and 30 g per day in the other. In another three-week period, they will consume the same foods, but with no fiber added. Major outcomes will include fermentability of the fiber, as assessed by measurement of breath hydrogen, as well as shifts in fecal bacteria. The caloric value of the fiber will be determined and metabolic measures related to blood glucose control and inflammation will also be taken.

Key facts

Study ID

NCT01518088

Run by

Ingredion Incorporated

People needed

20

Starts

2012-02-01

Expected to finish

2013-12-01

Last updated by the study team

2016-04-21

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Body mass index from 25 to 35 kg/m2.
• Willing to consume study foods and comply with dietary exclusions and specimen collection

You may not qualify if…

• Pregnancy
• Diabetes
• Gastrointestinal disease
• Regular use of pre- or probiotics
• Recent use of antibiotics
• High intake of dietary fiber

Where it is running

• USDA, ARS, Western Human Nutrition Research Center — Davis, California, United States

Full record on ClinicalTrials.gov

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