Pharmacological Approach to Improve the Outcome of Social Cognition Training

Completed · Phase 1 · Has a placebo group

Conditions studied: Schizophrenia

In brief

This study will evaluate whether oxytocin will facilitate the learning of social cognitive skills in schizophrenia patients who receive 12 sessions of Social Cognitive Skills Training (SCST). The primary hypothesis is that schizophrenia subjects who are treated with oxytocin will demonstrate greater improvements in a summary measure of social cognition than subjects treated with placebo over the course of SCST.

Key facts

Study ID

NCT01517360

Run by

VA Greater Los Angeles Healthcare System

People needed

27

Starts

2012-01-01

Expected to finish

2013-02-01

Last updated by the study team

2013-03-29

Who can join

Age: 18 and older, up to 55. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders 4th edition
• Stable on an antipsychotic medication
• No change in antipsychotic dose of >10% during the past 3 months

You may not qualify if…

• Unable to provide informed consent
• History of epilepsy
• Active medical conditions that would make the study unsafe
• History of serious head injury
• History of hyponatremia

Where it is running

• West Los Angeles VA Medical Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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