Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation

Completed · Phase 4

Conditions studied: Asthma

In brief

The purpose of this study is to evaluate the effectiveness of nebulized magnesium sulfate as a vehicle for albuterol in children with moderate to severe asthma exacerbation.

Key facts

Study ID

NCT01515995

Run by

University of Texas Southwestern Medical Center

People needed

50

Starts

2012-01-01

Expected to finish

2015-10-01

Last updated by the study team

2019-02-21

Who can join

Age: 7 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients age ≥ seven years
• Previous diagnosis of asthma or previous episode of wheezing treated with beta-agonist medication
• Able to complete bedside spirometry
• FEV1 < 70% predicted

You may not qualify if…

• Known allergy to magnesium sulfate
• Known contra-indication to albuterol
• Respiratory distress occurring as a result of bedside spirometry
• History of neuromuscular disease, cardiac disease, renal disease, or underlying chronic lung disease
• Pregnancy
• Use of oral steroid medication within 72 hours of presentation
• Radiographic evidence of pneumonia at presentation
• Intubation during the current encounter prior to study enrollment
• Administration of intravenous magnesium sulfate prior to study enrollment
• Prior participation in this study

Where it is running

• Children's Medical Center Dallas — Dallas, Texas, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.