Effect of Blueberries on Cognition and Body Composition in Elderly With Mild Cognitive Decline

Completed · Not applicable · Has a placebo group

Conditions studied: Mild Cognitive Decline

In brief

Purpose: The purpose of this study is to examine the effect of blueberry consumption on cognitive decline and body composition in humans. Hypothesis 1: Adults with mild cognitive decline who consume blueberries will experience an improvement in cognitive abilities as measured by a standardized battery of tests, relative to those who consume a placebo. Hypothesis 2: Adults with mild cognitive decline who consume blueberries will evidence an increase in processing speed and an improvement in memory abilities as measured in an electrophysiological paradigm and compared to those who consume a placebo. Hypothesis 3: Daily intake of 35 g freeze-dried blueberries will improve body composition (fat mass vs. lean mass). Hypothesis 4: Daily intake of 35 g freeze-dried blueberries will decrease oxidative stress and inflammatory markers.

Key facts

Study ID

NCT01515098

Run by

University of North Carolina, Chapel Hill

People needed

123

Starts

2012-01-01

Expected to finish

2015-03-01

Last updated by the study team

2022-03-08

Who can join

Age: 65 and older, up to 79. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Men and women age 65 and older
• BMI between 18.5 and 34.5
• Close individual to report memory decline

You may not qualify if…

• History of central nervous system or psychiatric disorders
• Dementia or Alzheimer's diagnosis
• Diabetes
• Smoking >20 cigarettes/day
• Gastrointestinal/digestive disorders
• Uncontrolled chronic disease

Where it is running

• Nutrition Research Institute — Kannapolis, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.