MRI-Guided Laser Induced Thermal Therapy

Stopped early

Conditions studied: Malignant Glioma

In brief

Does MR-guided laser interstitial thermal therapy (MRgLITT) prior to chemotherapy and/or radiation give patients a beneficial increase in overall survival? Laser induced thermal therapy (LITT) is a minimally invasive procedure for destroying tissue through generation of heat.

Key facts

Study ID

NCT01515085

Run by

Rutgers, The State University of New Jersey

People needed

1

Starts

2011-08-01

Expected to finish

2012-06-01

Last updated by the study team

2014-05-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects that have/will undergo MRgLITT for inoperable brain tumor.
• Tumor size < 3cm in transverse diameter for each planned applicator placement.
• Tumor size < 4 cm in largest dimension.
• Lesion(s) are clearly defined on pre-therapy contrast enhanced MRI scans as determined by the treating surgeon.
• Karnofsky Performance Scale score > 70.
• ECOG performance status of 2 or better.
• Biopsy proven histologic diagnosis of malignant glioma.

You may not qualify if…

• Patients with co-existing medical conditions with life expectancy < 1 year.
• Patients having received pre-ablation chemotherapy and/or radiation to lesion.

Where it is running

• Robert Wood Johnson University Hospital — New Brunswick, New Jersey, United States

Full record on ClinicalTrials.gov

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