Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study

Completed · Not applicable · Has a placebo group

Conditions studied: Aphasia, Stroke

In brief

In this study the investigators will examine the efficacy of navigated excitatory repetitive transcranial magnetic stimulation (nerTMS) for the treatment of post stroke aphasia. The investigators expect that this new types of rehabilitation (nerTMS) will help patients with aphasia return to their lives as they were prior to the stroke.

Key facts

Study ID

NCT01512264

Run by

University of Alabama at Birmingham

People needed

28

Starts

2012-01-01

Expected to finish

2018-07-20

Last updated by the study team

2020-07-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• LMCA stroke as indicated by the presence of aphasia and MRI lesion in the LMCA distribution
• Moderate aphasia (Token Test score between 40th and 90th percentile)
• Fluency in English
• Provision of written informed consent by the patient and/or the next of kin

You may not qualify if…

• Age less than 18 years
• Underlying degenerative or metabolic disorder or supervening medical illness
• Severe depression or other psychiatric disorder
• Positive pregnancy test in women of childbearing age
• Any contraindication to MRI/fMRI at 3T (i.e., intracranial metal implants, claustrophobia)
• Any contraindication to nerTMS (e.g., seizures or epilepsy)

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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