The Effects of HMB, ATP, and HMB Plus ATP on Muscle Mass, Strength, and Power in Resistance Trained Athletes

Completed · Not applicable · Has a placebo group

Conditions studied: Healthy Experienced Weight Training Males

In brief

The purpose of this study is to * determine the effects of 12 weeks of HMB free acid gel, ATP, and HMB free acid gel plus ATP supplementation in trained individuals during a periodized training program on skeletal muscle hypertrophy, body composition, strength, force, velocity, and peak power during loaded and unloaded vertical jumps. Additionally, the study will determine if either supplementation protocol prevents the typical decay seen in performance following an overreaching cycle performed in the 9th and 10th weeks of the study. Finally, the study will elucidate the mechanisms of action of supplementation on protein breakdown by analyzing serum indices of muscle damage (CK, LDH) and anabolic status (Testosterone:Cortisol ratio) as well as a urinary indicator of protein breakdown (3-methylhistidine). We hypothesize that under these conditions that the supplementation protocols will augment skeletal muscle hypertrophy, strength, and power and that HMB will blunt increases in serum indices of muscle damage, and urinary indices of protein breakdown.

Key facts

Study ID
NCT01508338
Run by
Metabolic Technologies Inc.
People needed
44
Starts
2012-01-01
Expected to finish
2012-10-01
Last updated by the study team
2017-08-01

Who can join

Age: 18 and older, up to 30. Sex: male. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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