Rhinological Outcomes in Endonasal Pituitary Surgery

Completed

Conditions studied: Pituitary Neoplasm, Pituitary Adenoma, Prolactinoma, Cushings Disease, Acromegaly

In brief

This is a prospective, multi-center observational study designed to address patient-reported nasal outcomes in adults undergoing endoscopic and microscopic surgical removal of pituitary tumors. The primary objective of this study is to determine the difference in nasal outcomes by using the Anterior Skull Base (ASK) Nasal survey between patients treated with endoscopic surgical technique and those treated with microscopic surgical technique. Patients will be given the ASK Nasal survey to assess their nasal functioning and overall health before their surgery, and at post-operative visits 1-2 weeks, 3 months, and 6 months.

Key facts

Study ID

NCT01504399

Run by

St. Joseph's Hospital and Medical Center, Phoenix

People needed

235

Starts

2011-10-01

Expected to finish

2015-12-09

Last updated by the study team

2018-08-22

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pituitary tumor patients treated by transsphenoidal route
• Adults (age 18-80 years)
• Direct endonasal or endoscopic approach
• Non-functioning adenoma, Cushing's disease, acromegaly

You may not qualify if…

• Patients treated by expanded endonasal approaches (transtubercular approach)
• Sublabial approach

Where it is running

• Barrow Neurological Institute/St. Joseph's Hospital and Medical Center — Phoenix, Arizona, United States
• John Wayne Cancer Institute at St. John's Health Center — Santa Monica, California, United States
• Northshore University Health System — Chicago, Illinois, United States
• Ohio State University Medical Center — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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