Multimodality Neuromonitoring in XLIF

Completed

Conditions studied: Degeneration of Lumbar Intervertebral Disc

In brief

This is a prospective, non-randomized multi-center study to evaluate intraoperative neuromonitoring results in subjects who undergo eXtreme Lateral Interbody Fusion (XLIF) surgery at any number of levels inclusive of L4-5.

Key facts

Study ID

NCT01499680

Run by

NuVasive

People needed

323

Starts

2011-10-01

Expected to finish

2014-06-01

Last updated by the study team

2025-12-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Persistent back and/or leg pain unresponsive to conservative treatment for at least six (6) months, unless surgical treatment is clinically indicated earlier
• Indicated for extreme lateral interbody fusion at any number of levels inclusive of L4-5
• At least 18 years of age at the date of written informed consent
• Able to undergo surgery based on physical exam, medical history and surgeon judgment
• Willing and able to return for post-treatment exams according to the follow-up called for in the protocol
• Signed and dated informed consent form

You may not qualify if…

• Patient has a mental or physical condition that would limit the ability to comply with study requirements
• Patient is a prisoner
• Patient is involved in active litigation relating to the spine (worker's compensation claim is allowed if it is not contested)
• Patient has an underlying neurological disease or neurological deficit that is not associated with the condition for which he/she is seeking surgical intervention (e.g., diabetic peripheral neuropathy)
• Patient is participating in another clinical study that would confound study data

Where it is running

• Shiley Center for Orthopaedic Research — La Jolla, California, United States
• UC Irvine Medical Center — Orange, California, United States
• Durango Orthopaedics — Durango, Colorado, United States
• USF Neurology and Neurosurgery — Tampa, Florida, United States
• West Augusta Spine Specialists — Augusta, Georgia, United States
• Georgia Spine and Neurosurgery Center — Decatur, Georgia, United States
• Pinnacle Orthopaedics and Sports Medicine — Marietta, Georgia, United States
• McLean Country Orthopedics — Bloomington, Illinois, United States
• Illinois Neurological Institute — Peoria, Illinois, United States
• Columbia Orthopaedic Group — Columbia, Missouri, United States
• Spine Midwest, Inc. — Jefferson City, Missouri, United States
• Western Regional Center for Brain and Spine Surgery — Las Vegas, Nevada, United States
• Duke University Medical Center — Durham, North Carolina, United States
• South Oregon Spine Care — Medford, Oregon, United States
• Univerisity of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States
• University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States
• Coastal Orthopaedic Associates — Conway, South Carolina, United States
• Spine Pain Be Gone Clinic — San Antonio, Texas, United States
• Caribbean Orthopaedic and Spine Institute — San Juan, PR, Puerto Rico
• Kantonsspital St. Gallen — Sankt Gallen, Switzerland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.