S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer
Completed · Phase 2
Conditions studied: Adenocarcinoma of the Gastroesophageal Junction, Esophageal Cancer, Gastric Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, leucovorin calcium, fluorouracil, irinotecan hydrochloride, and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Combining more than one drug may kill more tumor cells. It is not yet known which regimen of combination chemotherapy is more effective in treating tumor cells. PURPOSE: This randomized phase II trial studies how well oxaliplatin, leucovorin calcium, and fluorouracil work compared to irinotecan hydrochloride and docetaxel in treating patients with esophageal cancer, gastric cancer, or gastroesophageal junction cancer.
Key facts
- Study ID
- NCT01498289
- Run by
- SWOG Cancer Research Network
- People needed
- 213
- Starts
- 2012-02-01
- Expected to finish
- 2019-09-19
- Last updated by the study team
- 2019-11-07
Who can join
Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
- Sutter Auburn Faith Hospital — Auburn, California, United States
- Alta Bates Summit Medical Center-Herrick Campus — Berkeley, California, United States
- Mills - Peninsula Hospitals — Burlingame, California, United States
- Sutter Davis Hospital — Davis, California, United States
- Los Angeles County-USC Medical Center — Los Angeles, California, United States
- University of Southern California/Norris Cancer Center — Los Angeles, California, United States
- Fremont - Rideout Cancer Center — Marysville, California, United States
- Memorial Medical Center — Modesto, California, United States
- Palo Alto Medical Foundation-Camino Division — Mountain View, California, United States
- Palo Alto Medical Foundation-Gynecologic Oncology — Mountain View, California, United States
- Sutter Cancer Research Consortium — Novato, California, United States
- University of California Medical Center At Irvine-Orange Campus — Orange, California, United States
- Palo Alto Medical Foundation Health Care — Palo Alto, California, United States
- Valley Medical Oncology Consultants — Pleasanton, California, United States
- Sutter Roseville Medical Center — Roseville, California, United States
- Sutter General Hospital — Sacramento, California, United States
- University of California at Davis Cancer Center — Sacramento, California, United States
- California Pacific Medical Center-Pacific Campus — San Francisco, California, United States
- Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California, United States
- Sutter Pacific Medical Foundation — Santa Rosa, California, United States
- Palo Atlo Medical Foundation-Sunnyvale — Sunnyvale, California, United States
- Tahoe Forest Cancer Center — Truckee, California, United States
- Sutter Solano Medical Center/Cancer Center — Vallejo, California, United States
- University of South Alabama Mitchell Cancer Institute — Mobile, Alabama, United States
Full record on ClinicalTrials.gov
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