Rapydan Topical Anaesthesia for Arterial Cannulation

Completed · Phase 4 · Has a placebo group

Conditions studied: Arterial Catheterization

In brief

Arterial catheterization is painful and is associated with patient stress and anxiety. Analgesia is usually provided by subcutaneous injection of local anesthetic. An alternative is topical anaesthesia, such as Rapydan which is a novel topical anesthetic patch containing 70 mg each of lidocaine and tetracaine. We therefore tested the hypothesis that Rapydan patch analgesia is non-inferior to subcutaneous local anesthetic.

Key facts

Study ID

NCT01494311

Run by

Medical University of Vienna

People needed

90

Starts

2011-03-01

Expected to finish

2011-10-01

Last updated by the study team

2013-03-18

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients having elective valve-replacement or coronary artery bypass grafting requiring arterial access before induction of anaesthesia.

You may not qualify if…

• analgesic use within 24 hours before surgery
• injury or infection at the planned puncture site
• known allergy to local anesthetics
• drug abuse
• alcoholism or psychiatric disorders
• childbearing potential without adequate birth control
• abnormal Allen's test

Where it is running

• Cleveland Clinic Department of Outcomes Research — Cleveland, Ohio, United States
• Medical University of Vienna — Vienna, Austria
• Population Health Research Institute, McMaster University — Hamilton, Ontario, Canada

Full record on ClinicalTrials.gov

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