A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma

Completed · Phase 2 · Has a placebo group

Conditions studied: Hypertension, Glaucoma, Open-Angle

In brief

This randomized, double-blind, placebo-controlled, multi-center study will evaluate the safety and the effect of RO5093151 on intraocular pressure in patients with ocular hypertension or open angle glaucoma. Patients will be randomized to receive oral doses of RO5093151 or placebo twice daily. The anticipated time on study treatment is 7 days with the possibility to extend to 28 days.

Key facts

Study ID

NCT01493271

Run by

Hoffmann-La Roche

People needed

31

Starts

2011-12-01

Expected to finish

2012-11-01

Last updated by the study team

2016-11-02

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients, at least 21 years of age, inclusive
• Diagnosis of ocular hypertension or primary open angle glaucoma in at least one eye
• Able to participate and willing to give informed consent

You may not qualify if…

• Presence of extreme narrow angle with complete or partial closure
• Progressive retinal or optic nerve disease from any cause other than glaucoma
• History or signs of penetrating ocular trauma
• Uncontrolled hypertension
• Clinically significant abnormalities in laboratory test results
• Positive test results on hepatitis B, hepatitis C, or HIV 1 and 2
• Kidney disease or dysfunction

Where it is running

• Study site — Morrow, Georgia, United States
• Study site — High Point, North Carolina, United States
• Study site — Mt. Pleasant, South Carolina, United States
• Study site — Sofia, Bulgaria
• Study site — Hradec Králové, Czechia
• Study site — Litomysi, Czechia
• Study site — Prague, Czechia
• Study site — Ústí nad Labem, Czechia
• Study site — Zlín, Czechia
• Study site — Budapest, Hungary
• Study site — Budapest, Hungary
• Study site — Esztergom, Hungary

Full record on ClinicalTrials.gov

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