Sinusitis in Children and the Nasopharyngeal Microbiome

Completed

Conditions studied: Sinusitis

In brief

The purpose of this study is to investigate the relationship between viral infections of the upper respiratory tract, perturbations of the nasopharyngeal microbiome in children, and the risk of acute bacterial sinusitis over a one year period. The investigators will determine the incidence of acute bacterial sinusitis post viral upper respiratory infection and identify the viral antecedent infections and other risk factors which predispose to infection and ultimately design strategies to reduce the burden of disease and antimicrobial resistance.

Key facts

Study ID

NCT01492868

Run by

University of Wisconsin, Madison

People needed

323

Starts

2012-01-01

Expected to finish

2017-06-01

Last updated by the study team

2018-05-08

Who can join

Age: 4 and older, up to 7. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children 4 to 7 years of age
• Healthy
• English-speaking parent/guardian -

You may not qualify if…

• Any underlying condition which would predispose them to the development of sinusitis including congenital or acquired immunodeficiencies
• Craniofacial abnormalities
• Cystic fibrosis
• Allergic rhinitis or a previous episode of chronic sinusitis.

Where it is running

• UW Pediatrics at 20 S. Park St — Madison, Wisconsin, United States
• UW Health West Towne Pediatrics — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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