Beat the Blues in Pregnancy Study - Transcranial Magnetic Stimulation
Completed · Not applicable · Has a placebo group
Conditions studied: Major Depressive Disorder
In brief
The purpose of this study is to determine if repetitive transcranial magnetic stimulation (TMS) will alleviate symptoms of major depressive disorder (MDD) in pregnant women. TMS uses electromagnetic impulses to encourage neurons in the brain to communicate more effectively with one another. Effective neuron communication is thought to lead to the lessening of depressive symptoms. In this study subjects require daily TMS treatment for approximately four weeks.
Key facts
- Study ID
- NCT01492309
- Run by
- University of Pennsylvania
- People needed
- 22
- Starts
- 2011-11-01
- Expected to finish
- 2017-01-01
- Last updated by the study team
- 2018-04-10
Who can join
Age: 18 and older, up to 39. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Subjects are capable of giving written informed consent and complying with all study procedures;
- Female age 18-39 years old at date of enrollment;
- Pregnant, weeks 14-34;
- Current Depressive Symptoms;
- No change in antidepressant medication at least two weeks prior to study entry if using an antidepressant.
You may not qualify if…
- Any alcohol or drug abuse/dependence over the 6 months prior to study entry;
- History of a seizure disorder in subject or first degree relative;
- Anti-psychotic, lithium, or anti-convulsant medications within 2 weeks of study enrollment;
- History of known brain lesions, or severe head trauma;
- Subjects with any metallic object implanted in the skull;
- Subjects with significant cardiac disease;
- Neurological or psychiatric disorders;
- Serious medical illnesses that may compromise patient safety or study conduct;
- Currently taking a drug with known potential for fetal toxicity;
- Previous pregnancy with an adverse fetal outcome;
- Current obstetrical complications
- Actively suicidal;
- History of depression unresponsive to treatment with electroconvulsive therapy (ECT).
Where it is running
- Penn Center for Women's Behavioral Wellness — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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