Integrated Diagnostics Characterization of Right Ventricular Diastolic Flow Dynamics in Pulmonary Arterial Hypertension

Completed

Conditions studied: Pulmonary Hypertension

In brief

Pulmonary hypertension (PH) is a condition in which high blood pressure develops in the lungs and right side of the heart. People with PH suffer from shortness of breath, chest pain, heart failure, heart rhythm problems, and fainting. PH is diagnosed using a test called a cardiac catheterization where blood pressure is measured directly using a tube placed in the right side of the heart and lung arteries. Because a cardiac catheterization is invasive, researchers are investigating ways to diagnose PH using imaging tests that are not invasive. The study will evaluate whether or not a magnetic resonance image (MRI) of the heart, and blood tests can detect PH.

Key facts

Study ID

NCT01491646

Run by

National Jewish Health

People needed

25

Starts

2010-11-01

Expected to finish

2013-10-01

Last updated by the study team

2020-10-22

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• previous diagnosis of PH by right heart catheterization
• RV diastolic dysfunction by echo
• normal RV systolic function
• age 18-75 years old
• no contraindication to MRI

You may not qualify if…

• absence of PH
• absence of RV diastolic dysfunction by echo
• RV systolic dysfunction
• age < 18 years
• contraindication to MRI
• pregnancy

Where it is running

• National Jewish Health — Denver, Colorado, United States

Full record on ClinicalTrials.gov

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