Bioavailability of Fish Oils: Emulsified Versus Capsular Triglyceride

Completed · Not applicable

Conditions studied: Healthy Adults

In brief

The primary objective of this investigation is to determine the relative percentage and rate of incorporation of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and total omega-3 (n-3) fatty acids after ingestion of 4 emulsified flavored triglyceride fish oil supplements versus an encapsulated triglyceride in defined plasma lipid pools. The primary endpoints to be evaluated include the fatty acid composition of plasma lipids before and after consumption of a single dose of emulsified triglyceride based fish oil and triglyceride of similar n-3 compositions in capsule form. The investigators will measure changes in plasma phospholipid, and chylomicron fatty acids.

Key facts

Study ID

NCT01488747

Run by

USDA Grand Forks Human Nutrition Research Center

People needed

19

Starts

2011-11-01

Expected to finish

2016-04-01

Last updated by the study team

2018-08-03

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adults ages 18 to 60.
• Body mass index between 22 and 32 kg/m2.
• Medical history (interview) demonstrating good health.
• Nonsmoker.
• Consumption of a typical American diet with no unusual dietary habits.
• Willingness to comply with the study protocol.
• Low reported n-3 intake (<100 mg/d) on the Omega-3 Checklist

You may not qualify if…

• Any active, uncontrolled medical problem.
• Consumption of essential fatty acid supplements within the past 6 months.
• Use of lipid lowering drugs.
• Fish consumption greater than 1 fish meal per week

Where it is running

• USDA Grand Forks Human Nutrition Research Center — Grand Forks, North Dakota, United States

Full record on ClinicalTrials.gov

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