Specialized Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Completed · Phase 1
Conditions studied: Lung Cancer
In brief
This phase I trial studies the side effects and the best dose of hypofractionated radiation therapy when given together with chemotherapy in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving hypofractionated radiation therapy together with chemotherapy may kill more tumor cells.
Key facts
- Study ID
- NCT01486602
- Run by
- Alliance for Clinical Trials in Oncology
- People needed
- 22
- Starts
- 2012-03-01
- Expected to finish
- 2018-01-16
- Last updated by the study team
- 2018-01-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Mayo Clinic Hospital — Phoenix, Arizona, United States
- Mayo Clinic Scottsdale — Scottsdale, Arizona, United States
- Moores University of California San Diego Cancer Center — La Jolla, California, United States
- University of Chicago — Chicago, Illinois, United States
- University of Maryland/Greenebaum Cancer Center — Baltimore, Maryland, United States
- Dana Farber Cancer Institute — Boston, Massachusetts, United States
- State University of New York Upstate Medical University — Syracuse, New York, United States
- University of North Carolina - Chapel Hill — Chapel Hill, North Carolina, United States
- Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States
- Rhode Island Hospital — Providence, Rhode Island, United States
- University of Vermont — Burlington, Vermont, United States
Full record on ClinicalTrials.gov
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