Prospective L-arginine Study

Stopped early · Phase 1

Conditions studied: Heart Transplant

In brief

HYPOTHESIS The investigators primary hypothesis is that peripheral endothelial function and exercise tolerance will be abnormal in the population of young heart transplant patients at baseline, and that each will show a trend towards improvement following a 12 week course of oral L-arginine, with regression towards the baseline following the 12 week washout period.

Key facts

Study ID

NCT01485757

Run by

University of Michigan

People needed

3

Starts

2011-07-01

Expected to finish

2015-07-01

Last updated by the study team

2017-01-10

Who can join

Age: 8 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• University of Michigan Pediatric Heart Transplant Clinic patient.
• Greater than or equal to 8 years of age.
• Heart transplant between 1 and 8 years prior to enrollment in the study

You may not qualify if…

• Relative hypotension for age
• Refusal to participate
• Inability to cooperate with Endo-PAT testing
• Pregnant or nursing women.
• Insulin dependent diabetes

Where it is running

• University of Michigan Pediatric Heart Transplant Clinic — Ann Arbor, Michigan, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.