L-Arginine, Vascular Response and Mechanisms

Completed · Phase 2 · Has a placebo group

Conditions studied: Hypertension, Diabetes

In brief

The purpose of the study is to employ the supplement L-arginine to test the hypothesis that activation of blood flow to the brain during cognitive tasks is regulated by nitric oxide in older subjects with diabetes mellitus and/or hypertension (high blood pressure).

Key facts

Study ID

NCT01482247

Run by

Brigham and Women's Hospital

People needed

25

Starts

2012-04-01

Expected to finish

2014-01-01

Last updated by the study team

2016-07-28

Who can join

Age: 70 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• diabetes and/or hypertension

You may not qualify if…

• alzheimers disease, dementia, stroke, active herpes, recent angina or heart attack

Where it is running

• Brigham and Women's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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