Effects of Omega-3 Fatty Acid Supplementation on Inflammatory Response in Multisystem Trauma Patients

Stopped early · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Multiple Trauma

In brief

This study will evaluate the effects of omega-3 fatty acid supplementation on inflammation in trauma patients. The main hypothesis is that such supplementation will reduce the presence of biomarkers of systemic inflammation, as compared to placebo

Key facts

Study ID

NCT01477697

Run by

University of Cincinnati

People needed

12

Starts

2011-06-01

Expected to finish

2012-11-01

Last updated by the study team

2013-02-25

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Multi-system blunt trauma patients
• Ages 18 through 65 years, inclusive
• Admission to ICU
• Nasogastric or nasoenteric feeding tube in place
• Intention of primary medical team to feed the patient enterally

You may not qualify if…

• Expected mortality within 48 hours
• Intracranial hemorrhage
• Pregnant or breast feeding
• Patient, surrogate, or physician not committed to full support
• Refractory shock
• Unable to obtain enteral access
• Presence of partial or complete mechanical bowel obstruction, or ischemia, or infarction
• Current total parenteral nutrition (TPN) use, or intent to use TPN within 7 days
• Current gastrointestinal bleeding
• Requirement for vasopressors

Where it is running

• University Hospital — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.