Enteral Nutrition as Stress Ulcer Prophylaxis in Critically Ill Patients.

Completed · Not applicable · Has a placebo group

Conditions studied: Gastrointestinal Hemorrhage, Clostridium Difficile Colitis

In brief

study is to determine if proton pump inhibitors plus enteral nutrition is superior to enteral nutrition alone as a stress ulcer prophylaxis strategy in critically ill patients in terms of incidence of overt and significant GI bleeding related to stress gastropathy.

Key facts

Study ID

NCT01477320

Run by

Mohamed Saad

People needed

124

Starts

2013-09-01

Expected to finish

2016-07-01

Last updated by the study team

2018-01-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older
• Admission to the medical ICU at University of Louisville Hospital or Jewish Hospital
• Expected need for mechanical ventilation > 48 hours
• No contraindication to EN within the first 24 hours after admission to the ICU

You may not qualify if…

• Evidence of active GI bleeding during current hospitalization prior to study entry
• Admission to ICU with primary diagnosis of burn injury
• Closed head injury or increased intracranial pressure
• Partial or complete gastrectomy
• Pregnancy or lactation

Where it is running

• University of Louisville hospital — Louisville, Kentucky, United States

Full record on ClinicalTrials.gov

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