Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome

Stopped early

Conditions studied: Polycystic Ovary Syndrome, Insulin Resistance, Insulin Sensitivity, Obesity, Pregnancy

In brief

The polycystic ovary syndrome (PCOS) affects about 10% of reproductive-age women. Women with PCOS are at a higher risk of gestational diabetes, which may lead to more pregnancy complications. It is unknown if there are factors that may predict which women are more at risk. The goal of this study is to evaluate the risk factors of gestational diabetes, such as dietary and physical activity factors, race, and how the body handles its own hormones during pregnancy. Our long term goal is to contribute in finding ways to successfully prevent gestational diabetes.

Key facts

Study ID

NCT01475565

Run by

Virginia Commonwealth University

People needed

2

Starts

2013-05-01

Expected to finish

2014-08-01

Last updated by the study team

2015-12-14

Who can join

Age: 18 and older, up to 40. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of PCOS prior to pregnancy
• 18-40 years of age
• Documented BMI 30-40 kg/m2 (within 3 months prior to pregnancy or within 8 weeks of gestation)
• Either of Caucasian or African-American decent by self report.
• Pregnant or attempting pregnancy

You may not qualify if…

• Preexisting Diabetes (impaired glucose tolerance will not be an exclusion criterion because of the high prevalence of impaired glucose tolerance in the PCOS population).
• Hemoglobin < 8 or hemoglobin <10 with symptoms of anemia.
• Use of tobacco, alcohol or illicit substances.

Where it is running

• Virginia Commonwealth University Medical Center — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.