Oral Contraceptives, Insulin Resistance and Cardiovascular Risk Profile in Pre-Menopausal Women

Completed · Phase 4

Conditions studied: Insulin Sensitivity, Cardiovascular Risk, Perimenopausal Disorder

In brief

Birth control pills are the most commonly used method of birth control. The purpose of this research study is to examine whether birth control pills change heart disease risk and how the body handles blood sugar when given to different women.

Key facts

Study ID

NCT01475513

Run by

Virginia Commonwealth University

People needed

47

Starts

2011-11-01

Expected to finish

2014-05-28

Last updated by the study team

2018-08-08

Who can join

Age: 18 and older, up to 35. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Premenopausal, regular-cycling women 18-35 years
• Either African-American or Caucasian (African-American and Caucasian women will be BMI-matched)
• non-smoker.

You may not qualify if…

• Diabetes
• Clinically significant pulmonary, cardiac, renal, hepatic, neurologic, psychiatric, infectious, and malignant disease
• Contraindications to oral contraceptive use (history of blood clots, heart attacks or stroke, vascular disease, coagulopathy, prolonged immobilization, breast cancer, migraine head-aches, major surgery within past 6 months, blood pressure >160/100 mmHg, pregnancy or lactation)
• Use of hormonal contraceptives, glucose-lowering medications, anti-hyperlipidemic, anti-hypertensive or other vasoactive drugs within previous 3 months

Where it is running

• Virginia Commonwealth University Medical Center — Richmond, Virginia, United States

Full record on ClinicalTrials.gov

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