Effect of Sedation on Diagnostic Injections
Completed · Not applicable
Conditions studied: Sacroiliac Joint Pain, Sympathetically Maintained Pain
In brief
Interventional pain procedures have diagnostic, prognostic and therapeutic value. It is well-documented that the reference standard for identifying a pain generator is a low-volume block performed with local anesthetic, with or without steroid. Many factors may increase the false positive (FP) rate of diagnostic and prognostic nerve blocks; however, the use of sedation is the most controversial and remediable. Proponents of sedation argue that it has little effect on the rate of positive diagnostic blocks, and may even reduce the false-negative rate. The purpose of this study is to determine the effect of intravenous sedation on pain relief and the "false-positive rate" after diagnostic nerve blocks.
Key facts
- Study ID
- NCT01472835
- Run by
- Johns Hopkins University
- People needed
- 73
- Starts
- 2011-03-01
- Expected to finish
- 2013-02-01
- Last updated by the study team
- 2016-12-15
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Chronic pain > 4 weeks but < 10 years in duration
- Suspected SI joint or sympathetically-maintained pain based on history and physical exam
- May benefit from a sacroiliac joint or sympathetic block
- Pain on 0-10 NRS scale > 3/10 in intensity
You may not qualify if…
- No previous interventional pain-alleviating injections for the same condition within the past 3 years
- Uncontrolled coagulopathy
- Pregnancy, which will be ruled out by a urine pregnancy test in women of childbearing age
- Allergy to contrast dye or amide local anesthetics
- Unstable medical or psychiatric condition (e.g. unstable angina, congestive heart failure or severe depression) that could preclude an optimal treatment response
- Systemic infection
- Age < 18 or > 75 years
Where it is running
- Johns Hopkins Blaustein Pain Treatment Center — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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