The Epidemiology of Ventricular Assist Device-Related Infections

Completed

Conditions studied: Congestive Heart Failure

In brief

Infections often occur after ventricular assist devices (VADs) are placed. These infections can be very serious. The goal of this study is to understand why these infections occur. Bacteria (germs) normally live on our skin and in our noses. After surgery, they can infect the VAD. The investigators will collect cultures of your skin and nose before and after surgery. The investigators will compare these bacteria to bacteria that cause infections. Their genes will be compared to see which ones help the bacteria cause infection.

Key facts

Study ID

NCT01471795

Run by

Icahn School of Medicine at Mount Sinai

People needed

150

Starts

2006-01-01

Expected to finish

2009-01-01

Last updated by the study team

2011-11-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age greater than or equal to 18 years.
• Approved by the institution's heart failure/transplant committee for VAD implantation, either as a bridge to cardiac transplantation or for destination therapy for end-stage heart failure.
• Signed informed consent, release of medical information, and HIPAA forms.
• Expectation of compliance with protocol procedures and study visit schedule.

Where it is running

• University of Alabama at Birmingham — Birmingham, Alabama, United States
• Sharp Memorial Hospital — San Diego, California, United States
• Advocate Christ Medical Center — Oak Lawn, Illinois, United States
• Jewish Hospital — Louisville, Kentucky, United States
• University of Michigan — Ann Arbor, Michigan, United States
• University of Minnesota — Minneapolis, Minnesota, United States
• Columbia Presbyterian Medical Center — New York, New York, United States
• Montefiore Medical Center — The Bronx, New York, United States
• Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States
• LDS Hospital — Salt Lake City, Utah, United States
• Sacred Heart Medical Center — Spokane, Washington, United States
• University of Wisconsin Hospital — Madison, Wisconsin, United States
• St. Luke's Medical Center — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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