Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study

Completed · Not applicable

Conditions studied: Parkinson's Disease

In brief

Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life. Unfortunately, there are no successful interventions to address these impairments. Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD. The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory. The investigator's goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.

Key facts

Study ID

NCT01469741

Run by

Washington University School of Medicine

People needed

74

Starts

2011-06-01

Expected to finish

2014-05-01

Last updated by the study team

2015-06-03

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participants will be males and females over age 50 who meet criteria for idiopathic typical PD, are Hoehn \& Yahr39 stage I-III (mild-moderate disease) and are treated with levodopa/carbidopa.

You may not qualify if…

• Possible dementia,
• treatment with certain medications that interfere with cognition (e.g., anticholinergics),
• change in medications over the study period, other neurological disorders, brain surgery (e.g., STN DBS),
• history of psychotic disorder or significant current psychiatric disorder, or any condition that would interfere with testing (e.g., vision problems).

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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