Genetic Assessment of Early to Late Macular Degeneration Study

Completed

Conditions studied: Age-related Macular Degeneration

In brief

The purpose of this study is to determine if polymorphisms at rs11200638 on HTRA1 and rs1061170 on CFH are associated with an accelerated progression to advanced AMD (wet AMD or GA) in patients with early AMD (soft confluent drusen\>120 microns ) in the study eye, and with either early AMD or advanced AMD in the non-study eye.

Key facts

Study ID

NCT01464710

Run by

Henry Ferreyra

People needed

170

Starts

2008-04-01

Expected to finish

2015-01-01

Last updated by the study team

2019-06-21

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects will be eligible if the following criteria are met:
• Ability to provide written informed consent and comply with study assessments for the full duration of the study
• Age > 45 years
• Disease related considerations
• Subjects with a diagnosis of advanced AMD in one eye (either CNV or geographic atrophy) and soft confluent drusen in the study eye OR subjects with bilateral large soft drusen.

You may not qualify if…

• Subjects with any other progressive retinal disease that may impair the physician's ability to assess the severity of AMD

Where it is running

• University of California, San Diego — La Jolla, California, United States
• California Retina Consultants — Santa Barbara, California, United States
• Medical Center Ophthalmology Associates — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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