Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness

Completed · Not applicable

Conditions studied: Acute Respiratory Failure

In brief

The objective of this study is to determine the effect of thiamine therapy on oxygen consumption in critically-ill patients. The investigators will evaluate this by measuring VO2 before and after thiamine administration in patients admitted to the ICU and requiring mechanical ventilation.

Key facts

Study ID

NCT01462279

Run by

Beth Israel Deaconess Medical Center

People needed

20

Starts

2011-09-01

Expected to finish

2012-10-01

Last updated by the study team

2018-01-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (age > 18 years) admitted to an ICU
• Mechanically ventilated

You may not qualify if…

• Unstable ventilator settings during measurement of VO2
• Temp > 100 at time of VO2 measurement
• FIO2 > 60%
• Endotracheal cuff leak, chest tube, or other evident source of air leak
• Thiamine supplementation within 24 hours prior to study enrollment

Where it is running

• Beth Israel Deaconess Medical Center (BIDMC) — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.