MRI Results in Dupuytren's Contracture Before and After Injection With Xiaflex

Completed · Phase 4

Conditions studied: Dupuytren's Disease

In brief

The purpose of this study is to determine the effects of XIAFLEX on your finger through MRI.

Key facts

Study ID

NCT01450397

Run by

Hospital for Special Surgery, New York

People needed

5

Starts

2011-03-01

Expected to finish

2012-02-01

Last updated by the study team

2017-04-17

Who can join

Age: 35 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subject has a diagnosis of Dupuytren's Disease affecting only the metacarpophalangeal joint of the 4th or 5th finger.
• Subject has only one finger affected by the disease.
• Patients will be 35 years of age of older.
• Patients will be able to read, speak, and understand English or have available adequate translation assistance and be able to provide voluntary written consent to participate.

You may not qualify if…

• Female patients who are nursing or pregnant, or plan to become pregnant during the treatment phase.
• Patient has a chronic muscular, neurological or neuromuscular disorder that affects the hands.
• Patient has known allergy to collagenase or any other excipient of Xiaflex.
• Patient has received any collagenase treatments before the first dose of Xiaflex.
• Patient with abnormal coagulation, including patients who have received anticoagulant medications other than low-dose aspirin within 7 days of the injection.

Where it is running

• Hosptial for Special Surgery — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.