Family Based Cognitive-Behavioral Treatment for Preschoolers With Obsessive Compulsive Disorder

Completed · Not applicable

Conditions studied: Obsessive Compulsive Disorder (OCD)

In brief

The purpose of this research study is to further investigate how well cognitive-behavioral psychotherapy works to reduce obsessive-compulsive symptoms in young children with obsessive-compulsive disorder (OCD). Cognitive-behavioral therapy has been shown to work well in youth with OCD and other anxiety disorders; however, there are only a few studies to date in preschool and young children with OCD. All children will have the option to receive 12 twice-weekly cognitive-behavioral psychotherapy sessions that are up to 60-minutes each. Randomly determined, half of all children will receive these sessions immediately following the pre-assessment and the remaining half will receive them after six weeks. The investigators expect that youth receiving the study-based therapy will show more improvement in OCD symptoms in six weeks in contrast to youth waiting to receive the therapy.

Key facts

Study ID

NCT01447966

Run by

University of South Florida

People needed

31

Starts

2011-05-01

Expected to finish

2014-03-01

Last updated by the study team

2014-03-26

Who can join

Age: 3 and older, up to 8. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets DSM-IV-TR for a primary diagnosis of OCD
• Minimum score of 8 on the CYBOCS compulsion scale
• Peabody Picture Vocabulary IV score of 80
• Able to attend biweekly appointments with a parent/guardian
• English Speaking

You may not qualify if…

• Current clinically significant suicidality
• engaged in suicidal behaviors within 6 months
• Peabody Picture Vocabulary IV score of 80
• Any change in established psychotropic medication (e.g., antidepressants, anxiolytics) within 4 weeks before study enrollment, any change in antipsychotics within 3 weeks prior to the screening assessment, any change in Prozac or Straterra within 6 weeks of study enrollment, and any change in alpha-2 agonists or stimulants within 1 week of study enrollment.
• Lifetime DSM-IV bipolar, schizophrenia or schizoaffective disorders; or Substance abuse in past 6 months.
• Absence of language
• Formal diagnosis of mental retardation or an autism spectrum disorder
• Unwillingness of parents to make the commitment to accompany their child for multiple study visits, unwillingness to take part in randomization, inability to attend sessions twice weekly as therapist availability allows, inability to attend assessment visits.
• Presence of a significant and/or unstable medical illness which might lead to hospitalization during the study.

Where it is running

• University of South Florida - Rothman Center for Neuropsychiatry — St. Petersburg, Florida, United States

Full record on ClinicalTrials.gov

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