A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee

Completed · Phase 2 · Has a placebo group

Conditions studied: Osteoarthritis of the Knee

In brief

To evaluate the safety and efficacy of ABT-652 in combination with a Non-steroidal Anti-inflammatory Drug (NSAID) compared to NSAID alone in adults with osteoarthritis (OA) of the knee.

Key facts

Study ID

NCT01444365

Run by

AbbVie (prior sponsor, Abbott)

People needed

202

Starts

2011-10-01

Expected to finish

2012-04-01

Last updated by the study team

2013-05-15

Who can join

Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of osteoarthritis (OA) of the knee joint and meeting American College of Rheumatology (ACR) Clinical and Radiographic criteria,
• Currently taking nonsteroidal anti-inflammatory drugs (NSAIDs) and still experiencing pain as per the protocol requirements.
• Willing to washout of analgesics and to follow treatment plan, visit schedules and study procedures.

You may not qualify if…

• Diagnosis of rheumatoid arthritis, autoimmune disorder, arthritis other than osteoarthritis involving the study joint, or other painful syndrome that could interfere with the assessment of pain at the study joint
• Any cardiac, respiratory, neurological, psychiatric disorder or any other medical condition or illness that is not well controlled with treatment

Where it is running

• Site Reference ID/Investigator# 61226 — Phoenix, Arizona, United States
• Site Reference ID/Investigator# 61221 — Phoenix, Arizona, United States
• Site Reference ID/Investigator# 61241 — Tucson, Arizona, United States
• Site Reference ID/Investigator# 61257 — Anaheim, California, United States
• Site Reference ID/Investigator# 61246 — Fresno, California, United States
• Site Reference ID/Investigator# 61242 — La Mesa, California, United States
• Site Reference ID/Investigator# 61204 — Long Beach, California, United States
• Site Reference ID/Investigator# 61258 — North Hollywood, California, United States
• Site Reference ID/Investigator# 61265 — Milford, Connecticut, United States
• Site Reference ID/Investigator# 61234 — DeLand, Florida, United States
• Site Reference ID/Investigator# 61213 — Ocala, Florida, United States
• Site Reference ID/Investigator# 61211 — Oldsmar, Florida, United States
• Site Reference ID/Investigator# 61217 — Orlando, Florida, United States
• Site Reference ID/Investigator# 61231 — Plantation, Florida, United States
• Site Reference ID/Investigator# 61245 — Tampa, Florida, United States
• Site Reference ID/Investigator# 61263 — Marietta, Georgia, United States
• Site Reference ID/Investigator# 61210 — Brockton, Massachusetts, United States
• Site Reference ID/Investigator# 61260 — Watertown, Massachusetts, United States
• Site Reference ID/Investigator# 61244 — Florissant, Missouri, United States
• Site Reference ID/Investigator# 61266 — St Louis, Missouri, United States
• Site Reference ID/Investigator# 61206 — Omaha, Nebraska, United States
• Site Reference ID/Investigator# 61223 — Salisbury, North Carolina, United States
• Site Reference ID/Investigator# 61273 — Cincinnati, Ohio, United States
• Site Reference ID/Investigator# 61228 — Oklahoma City, Oklahoma, United States
• Site Reference ID/Investigator# 61264 — Portland, Oregon, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.